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KMID : 0359920110300040404
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Korean Journal of Nephrology
2011 Volume.30 No. 4 p.404 ~ p.408
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Minimal Change Nephrotic Syndrome Developed after Thymectomy in a Patient with Thymoma
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Doh Fa-Mee
Jang Seon-Jung
Shin Hye-Sun
Han Seung-Hyeok
Kang Shin-Wook
Koo Hyang-Mo
Kim Eun-Jin
Choi Kyu-Hun
Yoo Tae-Hyun
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Abstract
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We report a case of patient with malignant thymoma, who developed nephrotic syndrome several years after thymectomy. This 38-year-old man was diagnosed as myasthenia gravis and malignant thymoma and underwent thymectomy in 2004. Tumor resection and systemic chemotherapy were performed after recurrence in pleura in 2006. He also took pyridostigmine to control his symptoms of myasthenia gravis after thymectomy. Four years later, even though there was no evidence of recurrence of thymoma, he developed a nephrotic syndrome and was diagnosed as a minimal change disease on renal biopsy. After pulse therapy with methylprednisolone followed by oral administration of prednisolone therapy, nephrotic syndrome was improved.
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KEYWORD
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Minimal change nephrotic syndrome, Portal vein, Thrombosis, Acute kidney injury
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